NEW DRUGS Mirvasco for Rosacea
ثبت نشده
چکیده
NEW DRUGS Mirvasco for Rosacea Brimonidine topical gel 0.33% (Mirvasco, Galderma) has been approved for the topical treatment of the facial erythema of rosacea in adults 18 years of age and older. Applied once daily, the medication reduces redness of the face and lasts up to 12 hours. An alpha2-adrenergic agonist, brimonidine appears to constrict the dilated facial blood vessels, which reduces the redness of rosacea. A pea-sized amount of gel is applied to the forehead, chin, nose, and each cheek. The drug’s approval was based on data collected from two phase 3 studies in which reductions in facial redness were greater with brimonidine than with the vehicle gel. In controlled clinical trials, adverse reactions included erythema, flushing, a burning sensation, and contact dermatitis. Clinicians should use caution when prescribing this gel in patients with depression, cerebral or coronary insufficiency, Raynaud’s phenomenon, orthostatic hypotension, thromboangiitis obliterans, scleroderma, Sjögren’s syndrome, or uncontrolled cardiovascular disease. Source: Galderma, August 26, 2013
منابع مشابه
Improvement of Rosacea Symptoms in a 62-year-old Man with the Treatment of Iranian Traditional Medicine
Background: Rosacea is a chronic inflammatory skin disease that affects 0.5–10% of the population. Common symptoms are redness and itching in the nose bridge area, especially cheeks. The cause is not completely understood but genetics, increased growth of bacteria in the small intestine, and increased activity of Demodex mites are considered responsible. There is no certain cur...
متن کاملRecent advances in the understanding and management of rosacea
Rosacea is a chronic relapsing inflammatory facial dermatosis. There are several known triggers but the pathogenesis remains unknown. Recent achievements in understanding this disease point to the importance of skin-environmental interactions. This includes physical and chemical factors, but also microbial factors. The impairment of the skin barrier function and the activation of the innate imm...
متن کاملDrug-Induced Rosacea-like Dermatitis.
Rosacea is a common, chronic cutaneous disorder with a prevalence of 0.5-10%, predominantly affecting women. The disease presents with a heterogeneous clinical picture characterized by transient flushing, persistent facial redness, telangiectasias, and, in more severe clinical forms, the presence of inflammatory papules and pustules in the central third of the face. Although its pathophysiology...
متن کاملCombination of new multifunctional molecules for erythematotelangiectatic rosacea disorder
BACKGROUND Rosacea, a common chronic skin disorder, is currently managed by patient education, pharmacological drugs, medical devices (laser and light therapies), and use of proper skin cares. Unfortunately, none of these actual treatments used alone or in combination is curative, and so we proposed a dermocosmetic active ingredient to mitigate some aspects of the rosacea and particularly for e...
متن کاملAARS Hot Topics Member Newsletter
New Medical Research Comparative Study Using Autologous Fat Grafts Plus Platelet-Rich Plasma 3 Draft Genome Sequence of an Erythromycin-Resistant Propionibacterium 4 Treatment effects of lysozyme-shelled microbubbles and ultrasound in inflammatory skin disease. 4 Inhibition of Propionibacterium acnes lipase activity by the antifungal agent ketoconazole. 5 Development and Sequential Analysis of ...
متن کامل